As part of an active scientific community that studies the DNA damage response (DDR) and its impact on cancer and aging, research in the lab of Matthias Altmeyer is aimed at elucidating cellular mechanisms of genome integrity maintenance and their deregulation in human disease. Here you can explore who we are and what we do. Welcome!

Mini-Review published in Frontiers in Genetics

PhD Fellowship awarded to Federico Teloni

We are proud to announce that our lab member Federico Teloni was awarded the prestigious Candoc PhD Fellowship from the University of Zurich for his project “Defining cancer-specific alterations in genome integrity maintenance”. Well done and all the best for the project!

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Mini-Review published in Frontiers in Genetics

Mini-Review published in Frontiers in Genetics

We contributed a mini-review to a Frontiers in Genetics research topic dedicated to “Ubiquitin and Ubiquitin-relative SUMO in DNA damage response”. Our article on “Interplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic Stress” is now online.

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Postdoctoral researchers and PhD students

Postdoctoral researchers and PhD students

Motivated applications from postdoctoral candidates with a strong track record and willing to apply for fellowships are always encouraged. PhD students are recruited through the Molecular Life Sciences and Cancer Biology Programs of the Life Science Zurich Graduate School.

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Current Research Highlights
The TONSL-MMS22L complex guides homologous recombination to post-replicative chromatin
Neither too much, nor too little – balancing DNA end resection for faithful repair
Also check out the special issue on genome biology in Molecular Cell
And our free featured article in Trends in Cell Biology

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